Supporting Evidence: each row in the Supporting Evidence table contains a unique, non-redundant, item of data (experimentally obtained or computationally inferred) supporting a given interaction. Experimentally obtained evidence are given as retrieved, i.e. unaltered, from the public repositories from which data were collated to populate HVint. Redundancy across records obtained from these public repositories is removed as follows: two lines of supporting evidence are considered identical if they hold the same annotation for Source and Target protein identifiers, Detection Method, Interaction Type and Primary Citation.
Nodes colour-coding: nodes are coloured according to their location in the extracellular virion particle. Cyan nodes indicate capsid or capsid-associated proteins, orange nodes indicate tegument proteins, and yellow nodes envelope proteins (both glycoproteins or non-glycoproteins). Grey nodes represent proteins that are not present in the extracellular virion particle, i.e. only expressed during intracellular stages of the infection. The annotation data to allocate nodes to virion layers was manually curated from Gene Ontology records and selected literature, for each virus species.
PPI selection based on edge confidence scores: confidence scores range from 0 to 1, inclusive.
PPI selection based on node identifier: at the moment, node selection requires UniProtKB identifiers to be provided. A lookup table mapping open reading frames and UniProtKB identifiers can be found here.